Neurophysiological
facts
The polysynaptic
reflex: The neuron-neuron connections are synaptic,
where there are axon-axon, axon-dendrite and dendrite-dendrite
connections all of them through the synapses. If one take into
account that there are less neurons then dendrites and synapses,
it follows that every neuron could be connected with less or
more other neurons, what is confirmed by the existence of so
called polysynaptic reflexes. The polysynaptic reflex, as that
one which is presented on Fig 1., consists of single sensory
afferent neurone A, which diverges on more spinothalamic polysynaptic
pathways B, C, D and E. These polysynaptic pathways, in general
case, consist of dif-ferent numbers of neurones, i.e. each pathway
contains more synaptic neurone connections. These spinothalamic
polysynaptic pathways could converge on a single (Fig 1.a) or
on more ef-ferent neurones (Fig. 1.b). In the case when more
pathways converge on a single efferent neurone there is prolonged
reaction of the efferent neurone, because it is prolonged the
arriving of the afferent nervous impulses along the pathways.
Namely, the nervous impulse which drives along the pathway with
smallest number of neurones and synaptic neurone connections
will arrive first at the synaptic connection with the efferent
neurone, while the time delays of the impulses from other pathways
depend on the number of neurones which they contain.
The segmental
therapy is
developed on the base of the findings concerning the referred
pain phenomenon. It is a pain therapy, which aim is to blockade
the pain of inner body structure by the treatment of the Heads
zones on which the referred pain is projected. The treatment
is accomplished by the local injections of subcutaneous depots
of particular medicaments into the appropriate dermotom (Heads
zone) of pain projection. Taking into account its evident functional
similarity with acupuncture, the segmental therapy could be considered
as an embryo of the some future Western variant of scientifically
based acupuncture, which has a completely satisfactory scientific
description. An embryo because, although it is known more then
one century, the segmental therapy is practically still at its
beginning. This means that there is not an evident relevant interest
for serious investigations of segmental therapy in the Western
medicine. Taking into account that it is scientifically confirmed,
with description which is based on the description of the referred
pain phenomenon, it follows that the development of the segmental
therapy in fact lies in the development of its medical practice.
The divergence
and convergence effect: Due to the existence of the multiple connections,
every nervous impulse driving along the particular neuron could
diverge on more neurons (the divergence effect), as well as impulses
from many neurons could converge to a particular single neuron
(the convergence effect). Therefore it is possible the situation
where numerous afferent neurons from the different viscera and
different peripheral dermotomes or other somatic structures converge
to a particular spinothalamic neuron. In this case, where a lot
visceral and somatic nervous fibbers are served by a single spinothalamic
neuron, it is possible the false allotting of the
visceral pain, which could be projected on some somatic -structure
as referred pain. The referred pain phenomenon will be considered
later.
The facilitation
effect: On
the figure 3 are represented two spinothalamic neurones (a,b),
one peripheral afferent neurone arriving from a particular dermotom
(c) and one afferent neurone arriv-ing from a particular viscera
(d), which diverges on both spinothalamic neurones through the
terminations (e) and (f). The pre-sence of the nervous impulses
in the termination (f) decrease the activation threshold potential
of spinothalamic neurone (b) for the impulses arriving along
the peripheral neurone (c), i.e. the impulses in the afferent
neurone (d), arriving from the viscera, facilitates the activities
of the afferent neurone (c). Therefore, if the neural impulses
are present in the visceral neurone (c), an underthreshold neural
activities in the peripheral neurone (c) excites the impulses
in the spinothalamic neurone (c), which transferred into the
brain give a perception of referred pain, mentioned above, which
is false allotted to the dermotom instead of to the viscera.
The referred
pain phenomenon
arises in the case when the viscera (inner somatic structure)
and the dermotom are innervated and supplied by the same spinal
cord segment. This cutaneous-viscera functional connection on
the neural level arises between the dermotom and viscera which
develop from same embryonic segment in the embryogenesis. For
example, the traditional example of referred pain is the projection
of the myocardial infarction pain on the left hand, which explanation
as basic assumption has the fact that the hart and the left arm
arise from the same embryonic segment. This allows to conclude
that the particular inner organ and the corresponding Heads
zone, which are supplied by the same spinal cord segment, can
be seen as a functional unit - the viscero-somatic reflex. The
activation of the somatic part of this reflex is enabled due
to the convergence and facilitation effect, which will be described
later. The convergence effect is responsible for referred pain
when the visceral and somatic neurons converge to same spinothalamic
neuron. As the somatic pain is more frequently then the somatic
pain, the brain makes the false allotting of the visceral pain
as somatic pain. On other side, the facilitation effect is responsible
for referred pain when the visceral neuron converge to two spinothalamic
neurons, where one of them is connected with the somatic afferent.
In this case the activation of the visceral neuron facilitates
the activation of the somatic neuron, even in the case when it
receives under threshold stimulation.

|
Neurophysiological
Basis of ABEFIT
By prof.
Lj. R. Malnik
ABEFIT is transcutaneous
therapy.
Generally, the accomplishment of any transcutaneous therapy includes
three main steps: the stimulation of the particular skin (cutaneous)
segments - dermotomes, the transfer of the stimulation toward
the particular parts of central nervous system (CNS in the further),
and the reactions of these parts which result by the pain blockade
or by the regulation of irregular functions caused by some diseases.
The most known such therapies are segmental therapy, where so
called Heads zones are stimulated, and many different acupuncture
doctrines (the classical acupuncture, auriculo, oral, nasal,
Su Jok, acupuncture etc.), all of them based on the stimulation
of the particular acupuncture points on the body skin. The finding
of any satisfactory scientific explanation of the segmental therapy
and acupuncture is obviously very complicate problem, because
it is impossible without perceiving the unknown mechanism of
health and homeostasis control, which involves the most complicate
systems of our organism, like the central and vegetal nervous
system, all viscera and glands, etc. Many collected empirical
data show that it is the multidisciplinary scientific problem
and therefore the subject of investigation in medicine, biology,
chemistry, physics etc.
The transfer of the external cutaneous stimulus toward the internal
CNS centers, which is manifested as a pain or painless perception,
has a few stages. The first one corresponds to the activation
of the sensory nervous terminations (receptors), i.e. to the
creation of the nervous impulse, due to the transformation of
the energy of the initially stimulus (mechanical, electric, chemical
etc.) in the chimio electric energy. The transmission of the
created nervous impulse toward the CNS centers is along the sensory
pathway which usually consists of three neurons. The first neuron
transfers the impulse from the stimulated dermotom toward the
spinal cord, the second neuron is connection between the marrow
with the cerebral trunk and thalamus and, finally, the third
neurons brings the impulse in the cortex. This mechanism is responsible
for the transduction of the acupuncture point or dermotom stimulation,
independently of that is it painful or not.
As it can be seen, the function of the nervous system is not
only to register the stimulus, which is caused by the changes
of the external conditions in the environment, but also to answer
to it using the efferent neurons and effectors. This answer means
the accomplishment of the basic function of the nervous system:
handling of the changes of external conditions and accommodation
to these changes. All these activities are functionally accomplished
through the particular reflex arches (reflexes only in the farther),
which include the following parts: sensory receptor, afferent
neuron, neurons which connect the afferent neuron with spinal
cord or brain control centers, efferent neuron and effector.
As the functions of the nervous systems could be completely accomplished
on different levels, the reflexes could be less or more complicate,
where the level depends on the type of the control centers included
in the reflex. The simple reflexes are accomplished on the spinal
cord level, the more complicate includes the hypothalamic control
centers, while the most complicate reflexes include the cortical
control centers as well.
Every neural reflex could be considered as a closed neuron loop,
which consists of a different number of neurons. However, the
particular reflex does not contains always the same set of neurons,
because the closure of the particular neuron loop is determined
by the synapses states on the way of the nervous impulse, which
passes through the most ready synapses, i.e. through the synapses
which are in the most appropriate state for impulse transfer.
Therefore, the different closing of the particular reflex, which
is activated by the stimulation of the particular dermotom, could
be effectuated through the different neuron loops with different
neurons and, even more, with different number of neurons end
synapses in the loop.
ABEFIT is
transcutaneous therapy which aim is to activate the polysynaptic
reflex with short and well defined spinothalamic neuron pathways
toward the homeostatic control centers in CNS. The essential facts about all transcutaneous
therapies (acupuncture, segmental therapy and this one) are not
in that what happen on the stimulated dermotomes but in the process
between them and the control centers in the CNS. Namely, there
are a lot empirical data which show that the transcutaneous therapy
could be successfully applied as pain therapy (analgesia effects),
having the aim to blockade the pain only, but there are also
the evidences that it is a kind of homeostatic therapy which,
acting on the homeostatic centers in CNS, drives the organism
into the homeostatic state. The pain is often the secondary manifestation
of the health problem, it even more must not be present, and
its blockade does not means that the health problem is solved.
Therefore, the most important and impressive results of any transcutaneous
therapy is not the analgesia effect, which demonstrates the efficiency
of its symptomatic therapeutic possibilities, but the healing
effects which are the evidence of the influence of acupuncture
on the homeostatic control system - the set of control systems
which are responsible for the homeostasis. Even more, the traditional five energies
theory of
acupuncture, which talks about the harmonization of the five
vital energies, is an attempt to describe the homeostatic effects
of acupuncture, where the homeostatic state is recognized as
an energetically balanced state. Therefore, or in accordance
with this, it is important to analyze the processes of the spinothalamic
divergence of the transcutaneous stimulation from the particular
dermotomes (acupuncture points, Heads zones), i.e. the
processes in which the stimulation of the sensory neuron diverges
in a polysynaptic reflex which activate more spinothalamic neurons
and transfer the nervous impulses toward more control centers
of CNS.
Any health problem or dysfunction in some particular part of
the human body is followed by the biochemical and physical processes,
which lead to the change of the local electric field potential.
If this change is equal or larger then the neuron threshold potential,
the neuron will be activated, i.e. the nervous impulse will be
created and the information toward the control centers in CNS
will be transferred. These impulses bring the informations about
the health problem, which is felt as pain or as some uneasiness,
and alarm the self-defense system of CNS, responsible for homeostasis,
to solve the problem using the efferent nerves, or some other
yet unknown mechanism. However, if the change of the local electric
field potential is smaller then the neuron threshold potential,
the neuron will be not activated and the control centers in CNS
will be not informed about the health problem. In this way, when
the self-defense system remains slipping, the cumulative effects
of such small changes could result in a grate health problems.
In the first case, the activated nervous impulses inform us,
by pain or uneasiness, that we have a health problem, while in
the second case we have, but we do not know that we have a health
problem. In accordance with this, one could conclude that there
are two kind of illnesses: 1)
Talkative
illness,
which talks, announces itself by pain or uneasiness transferred
in the CNS by the activated neuron reflexes; 2) Silently
illness,
which is silent and hidden for CNS, because of the underthreshold
changes of the local electric field potential. This means that
the most complete transcutaneous treatment, which is prevention
and healing in the same time, is that one which enable the activation
of the control centers of CNS to scan and correct any dysfunction,
independently of the changes of the local electric field potential
caused by it.
Thus, the question is: is it possible to activate
the control centers of CNS by the transcutaneous stimulation,
in order to scan and heal the talkatives and silentlies illnesses
and to return back the organism in a homeostatic state, or as
near as it is possible? The answer is obviously positive, what could
be supported by the neurophysiological facts. The most important
neurophysiological proof lies in the possibility of exciting
the polysynaptic reflexes, where the transcutaneous stimulation
diverges in more spinothalamic neurons, what enables the transfer
of the nervous impulses toward more control centers in CNS. These
polysynaptic reflexes could be excited due to the spinothalamic
divergence effect of the transcutaneous stimulation.
There are not the neurophysiological obstacles that polysynaptic
reflexes with the spinothalamic divergence of the transcutaneous
stimulation could appear, but the question is how to determine
acupuncture points or skin zones which stimulation obviously
excite such reflexes? As it is practically impossible to find
the answer on this question remaining in the frames of neurophysiology,
it is worth to look for it considering the empirical results,
among others the practical results of the traditional alternative
medical doctrines. In spite of the millenniums which are behind,
many results and recipes of these doctrines, including the acupuncture,
must be taken with suspicion. Thus, taking into account that
is very complicate to investigate all possible interconnections
and combinations of 400 acupuncture points, and the effect of
multiple referred pain projections, it is quite plausible to
assume that some of these acupuncture point are functionally
equivalent. The neurophysiological findings, like the polysynaptic
reflexes, as well as the divergence and/or facilitation effect
show that the answer should be positive. The next supports to
the positive answer are the results and the efficiency of microacupuncture
doctrines which use more less then 400 acupuncture points, even more not included in the mentioned
WHO nomenclature. The illustrative example is the efficiency
of the Su Jok 6 Qi energies therapy, where the complete energy
balance (homeostasis!) could be achieved by the stimulation of
these 6 acupuncture points only which are on the hands. What
we would like to do here is neither to discuss the acceptance
or refusing of this doctrine, nor to explore its theoretical
background, but to try to find the neurophysiological explanation
of its practical efficiency and to modify it in a way which will
enable the effective activation of the homeostatic control centers
in CNS. There are some scientific - neurophysiological data,
as well as many scientifically unsupported empirical results
to pay the attention to this doctrine, which is, even more, not
traditional but the new one, because it is founded a couple decades
ago In fact, the searching for the most appropriate way of transcutaneous
stimulation which could activate the polysynaptic reflex with
spinothalamic neuron pathways being able to reach up and to activate
the homeostatic control centers in CNS brought in my field of
interest the Su Jok 6 Qi energies therapy.
From the neurophysiological point of view, the hands are very
reach with nervous ends, what procures very effective transcutaneous
stimulation, which is transferred toward the spinothalamic nerves
in the spinal cord by the nerves radialis, medianis and ulnaris (on the Fig. 4. the skeen
zones inervated by these nerves are presented). As these nerves
enter in the sacral part of the spinal cord, that means very
near to the brain, it is maximal the possibility that the polysinaptic
reflex, consisting of more spinothalamic neurons and activated
by the nervous impulses which bring these three nerves, will
be able to reach up and to activate the control centers in CNS.
Namely, the divergence and facilitation effects make possible the creation, but also the partial or complete
extinguishment of the polysynaptic reflex. Therefore the shorter
pathways of the polysynaptic reflex in spinal cord increase the
possibility that they will reach up and activate the control
centers. If one accept that the dermotomes on the hands are probably
the most appropriate for transcutaneous stimulation which could
activate the polysynaptic reflex with short and well defined
spinothalamic neuron pathways toward the homeostatic control
centers in CNS, then the practice rules and the empirical results
of the Su Jok 6 Qi energies therapy must not be neglected. That
therapy is in fact a correspondent Hindu chakra system, because
the correspondences between 6 chakras and 6 particular acupuncture
points on the hand have been established. The main aim of the
therapy is the energy balance (homeostasis) which could be achieved
by the appropriate stimulation of these points, what is equivalent
to the stimulation of the corresponding chakras. More precisely,
the Su Jok 6 Qi energies therapy uses 24 acupuncture points,
6 points on the palm sides and 6 points on the opposite sides
of the hands, what means that 4 points correspond to each energy
and to each chakra. Which 6 points, i.e. which hand and which
side should be stimulated
is determined
by the practice rules which will be omitted here as doubtful
with no hope to be scientifically supported. However, the practical
results show that the positions of these points coincide with
the positions of dermotomes which we are looking for, enabling
the activation of the polysynaptic reflex with well defined neuron
pathways toward the homeostatic control centers in CNS. |